Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2097144 | 0.82 | — | — | |
| Methane SCHEMBL28702012 | 0.67 | — | — | |
| Methane SCHEMBL31369160 | 0.67 | — | — | |
| Methane SCHEMBL27283826 | 0.67 | — | — | |
| Methane SCHEMBL9435911 | 0.67 | — | — | |
| Methane SCHEMBL23040988 | 0.67 | — | — | |
| Methane SCHEMBL5586176 | 0.67 | — | — | |
| Methane SCHEMBL1162076 | 0.67 | — | — | |
| Methane SCHEMBL11592345 | 0.67 | — | — | |
| Methane SCHEMBL27360109 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032242-A | Titanium diboride/boron carbide composites with high hardness and toughness | THE DOW CHEMICAL COMPANY (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0383763-A4 | TITANIUM DIBORIDE/BORON CARBIDE COMPOSITES WITH HIGH HARDNESS AND TOUGHNESS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4957884-A | Titanium diboride/boron carbide composites with high hardness and toughness | THE DOW CHEMICAL COMPANY (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0383763-A1 | TITANIUM DIBORIDE/BORON CARBIDE COMPOSITES WITH HIGH HARDNESS AND TOUGHNESS | THE DOW CHEMICAL COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| WO-1988008328-A1 | TITANIUM DIBORIDE/BORON CARBIDE COMPOSITES WITH HIGH HARDNESS AND TOUGHNESS | THE DOW CHEMICAL COMPANY (US) | 1988-11-03 | — | — | WO | disclosed |