Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | THPO | P40225 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765719 | 1.00 | SLC29A1 (0.68) | SLC29A1ADORA2ATSHRTHPOPMP22 | |
| SCHEMBL9765738 | 0.99 | SLC29A1 (0.69) | SLC29A1ADORA2ATSHRTHPOPMP22 | |
| SCHEMBL9765721 | 0.99 | SLC29A1 (0.69) | SLC29A1ADORA2ATSHRTHPOPMP22 | |
| SCHEMBL9765756 | 0.89 | SLC29A1 (0.69) | SLC29A1ADORA2ATSHRTHPOADORA1 | |
| SCHEMBL9765745 | 0.89 | SLC29A1 (0.69) | SLC29A1ADORA2ATSHRTHPOADORA1 | |
| SCHEMBL899687 | 0.86 | SLC29A1 (0.79) | SLC29A1ADORA2ATSHRTHPOADORA1 | |
| SCHEMBL17470300 | 0.86 | SLC29A1 (0.79) | SLC29A1ADORA2ATSHRTHPOADORA1 | |
| SCHEMBL20579787 | 0.86 | SLC29A1 (0.79) | SLC29A1ADORA2ATSHRTHPOADORA1 | |
| SCHEMBL29364428 | 0.86 | SLC29A1 (0.79) | SLC29A1ADORA2ATSHRTHPOADORA1 | |
| SCHEMBL16010153 | 0.86 | SLC29A1 (0.79) | SLC29A1ADORA2ATSHRTHPOADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055569-A | Gastrointestinal disorders | G. D. SEARLE & CO. (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0423777-A2 | Method of treating gastrointestinal motility disorders | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |
| EP-0423776-A2 | N-(6)-substituted adenosine compounds | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |