Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | THPO | P40225 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765756 | 1.00 | SLC29A1 (0.69) | SLC29A1TSHRADORA1ADORA3ADORA2A | |
| SCHEMBL9765738 | 0.90 | SLC29A1 (0.69) | SLC29A1TSHRADORA1ADORA3ADORA2A | |
| SCHEMBL9765721 | 0.90 | SLC29A1 (0.69) | SLC29A1TSHRADORA1ADORA3ADORA2A | |
| SCHEMBL9765719 | 0.89 | SLC29A1 (0.68) | SLC29A1TSHRADORA1ADORA3ADORA2A | |
| SCHEMBL9765704 | 0.89 | SLC29A1 (0.68) | SLC29A1TSHRADORA1ADORA3ADORA2A | |
| SCHEMBL29364428 | 0.87 | SLC29A1 (0.79) | SLC29A1TSHRADORA1ADORA3ADORA2A | |
| SCHEMBL899687 | 0.87 | SLC29A1 (0.79) | SLC29A1TSHRADORA1ADORA3ADORA2A | |
| SCHEMBL20579787 | 0.87 | SLC29A1 (0.79) | SLC29A1TSHRADORA1ADORA3ADORA2A | |
| SCHEMBL17470300 | 0.87 | SLC29A1 (0.79) | SLC29A1TSHRADORA1ADORA3ADORA2A | |
| SCHEMBL16010153 | 0.87 | SLC29A1 (0.79) | SLC29A1TSHRADORA1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055569-A | Gastrointestinal disorders | G. D. SEARLE & CO. (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0423777-A2 | Method of treating gastrointestinal motility disorders | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |
| EP-0423776-A2 | N-(6)-substituted adenosine compounds | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |