Urea

Urea

SCHEMBL9765776

C=C(C)C.CN(C)C(N)=O.NC(N)=O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.47
LMNA P02545 2/20 0.41
PMP22 Q01453 2/20 0.41
ALOX15 P16050 1/20 0.41
BLM P54132 1/20 0.41
ALDH1A1 P00352 3/20 0.38
OR51E2 Q9H255 1/20 0.38
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.32
NFKB1 P19838 1/20 0.32
THPO P40225 1/20 0.32
MAPT P10636 1/20 0.32
APEX1 P27695 1/20 0.32
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL1073077 0.87 ALDH1A1 (0.50) TDP1LMNAPMP22ALOX15BLM
SCHEMBL27862548 0.83
Ethylene SCHEMBL8978437 0.83
SCHEMBL75527 0.83
Urea SCHEMBL223244 0.83
SCHEMBL21811 0.83
SCHEMBL27985624 0.83 ALDH1A1 (0.47) TDP1LMNAPMP22ALOX15BLM
SCHEMBL3890759 0.79
Hydrogen Peroxide SCHEMBL4372518 0.79
SCHEMBL3889888 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021294-A For examining specimen BIOMATE CO., LTD. (JP) 1991-06-04 US disclosed