Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | MAP3K13 | O43283 | 2/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200061 | 0.89 | GPR119 (0.61) | GPR119HDAC1PARP1HSD11B1RET | |
| SCHEMBL1200066 | 0.89 | GPR119 (0.61) | GPR119HDAC1PARP1HSD11B1RET | |
| SCHEMBL1200065 | 0.89 | GPR119 (0.61) | GPR119HDAC1PARP1HSD11B1RET | |
| SCHEMBL12740842 | 0.89 | GPR119 (0.64) | GPR119HDAC1PARP1HSD11B1RET | |
| SCHEMBL12740858 | 0.89 | GPR119 (0.61) | GPR119HDAC1PARP1HSD11B1RET | |
| SCHEMBL30510788 | 0.88 | GPR119 (0.58) | GPR119HDAC1PARP1HSD11B1RET | |
| SCHEMBL24467689 | 0.87 | GPR119 (0.59) | GPR119HDAC1PARP1HSD11B1RET | |
| SCHEMBL18339875 | 0.86 | GPR119 (0.58) | GPR119HDAC1PARP1HSD11B1RET | |
| SCHEMBL29877240 | 0.85 | GPR119 (0.57) | GPR119HDAC1PARP1HSD11B1RET | |
| SCHEMBL1200864 | 0.85 | GPR119 (0.60) | GPR119HDAC1PARP1HSD11B1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994460-A | Treatment or prevention of disorders resulting from central nervous system anoxia | BRISTOL-MYERS SQUIBB CO. (US) | 1991-02-19 | — | — | US | disclosed |