SCHEMBL9766009

SCHEMBL9766009

[CH2]c1c(OC)c(F)c(OC)c(F)c1OC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9766091 0.89 HSD17B10 (0.33) HSD17B10
SCHEMBL9766062 0.83
SCHEMBL1073796 0.82 HSD17B10 (0.35) HSD17B10
SCHEMBL3763099 0.77 HSD17B10 (0.41) HSD17B10
SCHEMBL9766097 0.74
SCHEMBL11369378 0.74 KDM4E (0.33)
SCHEMBL182607 0.74 HSD17B10 (0.40) HSD17B10
SCHEMBL16071629 0.73 HSD17B10 (0.32) HSD17B10
SCHEMBL16059218 0.71 HSD17B10 (0.39) HSD17B10
SCHEMBL1711725 0.69 HSD17B10 (0.47) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0266947-B1 HALOGENATED ESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-12-04 EP claimed
EP-0266947-A2 Halogenated esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP claimed
EP-0266947-B1 HALOGENATED ESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-12-04 EP disclosed
US-4853414-A 1-/2-ALKOXY-3,5-DIFLUOROBENZYL ESTERS OF 2,2-DIMETHYL-3-ALKYLCYCLOPROPIONIC ACID; INSECTICIDES; PESTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-08-01 US disclosed
EP-0266947-A2 Halogenated esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP disclosed