Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HK2 | P52789 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437139 | 0.90 | ALDH2 (0.42) | ALDH2PTGS2PDE4BKMT2APOLB | |
| SCHEMBL6672818 | 0.71 | PTGS2 (0.72) | PTGS2PTGS1ALDH1A1ABCB11MT-CO2 | |
| Bromide SCHEMBL9766218 | 0.70 | ALDH2 (0.46) | ALDH2PTGS2PDE4BKMT2APOLB | |
| SCHEMBL28257026 | 0.63 | PDE4B (0.54) | PTGS2PDE4BKMT2ALMNAALDH1A1 | |
| SCHEMBL7258464 | 0.63 | PDE4B (0.54) | PTGS2PDE4BKMT2APOLBLMNA | |
| SCHEMBL20121190 | 0.63 | PDE4B (0.54) | PTGS2PDE4BKMT2ALMNAALDH1A1 | |
| SCHEMBL20161110 | 0.63 | PDE4B (0.54) | PTGS2PDE4BKMT2ALMNAALDH1A1 | |
| SCHEMBL6348979 | 0.63 | PTGS2 (0.71) | ALDH2PTGS2PDE4BKMT2APOLB | |
| SCHEMBL10684202 | 0.63 | PTGS2 (0.55) | PTGS2PDE4BKMT2AMEN1LMNA | |
| SCHEMBL28460097 | 0.62 | PDE4B (0.46) | PTGS2PDE4BKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064649-A | CEPHALOSPORIN DERIVATIVES | BEECHAM GROUP P.L.C. (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0359536-A2 | Cephalosporin compounds, process for their preparation and pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1990-03-21 | — | — | EP | disclosed |