Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514267 | 0.97 | MEN1 (0.50) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL1000860 | 0.88 | MEN1 (0.46) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL999017 | 0.88 | MEN1 (0.46) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL1486144 | 0.88 | MEN1 (0.46) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL8500219 | 0.88 | MEN1 (0.46) | MEN1GAAKMT2ATDP1MAOA | |
| Water SCHEMBL6670447 | 0.86 | MEN1 (0.45) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL5041833 | 0.85 | MEN1 (0.51) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL5840460 | 0.83 | MEN1 (0.46) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL6234096 | 0.83 | TDP1 (0.49) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL27003866 | 0.82 | MEN1 (0.43) | MEN1GAAKMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045478-A | Vesicles and use thereof in an assay | BECTON DICKINSON AND COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| US-4828982-A | Vesticles and use thereof in an enzyme assay | BECTON, DICKINSON & COMPANY (US) | 1989-05-09 | — | — | US | disclosed |
| US-4717676-A | Vesicles and use thereof in an assay | BECTON DICKINSON AND COMPANY (US) | 1988-01-05 | — | — | US | disclosed |