Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514267 | 0.86 | MEN1 (0.50) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL12201805 | 0.84 | TDP1 (0.44) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL4001822 | 0.83 | TDP1 (0.56) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL9766290 | 0.83 | MEN1 (0.47) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL959018 | 0.83 | TDP1 (0.50) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL12656066 | 0.82 | TDP1 (0.61) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL25827367 | 0.82 | GAA (0.58) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL15244383 | 0.81 | TDP1 (0.50) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL5041833 | 0.81 | MEN1 (0.51) | TDP1MAOAMAOBGAAMEN1 | |
| SCHEMBL27801417 | 0.81 | TDP1 (0.50) | TDP1MAOAMAOBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |