Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9766359 | 0.91 | SIRT2 (0.36) | PTPN1ACP1CDC25BSIRT2TP53 | |
| SCHEMBL14603013 | 0.88 | EPHX2 (0.38) | SIRT2CETPCA2CA1 | |
| SCHEMBL12905097 | 0.88 | EPHX2 (0.38) | SIRT2CETPCA2CA1 | |
| SCHEMBL10231022 | 0.88 | EPHX2 (0.38) | SIRT2CETPCA2CA1 | |
| SCHEMBL25392805 | 0.86 | TSHR (0.40) | PTPN1ACP1CDC25BSIRT2CETP | |
| SCHEMBL25390831 | 0.86 | TSHR (0.40) | PTPN1ACP1CDC25BSIRT2CETP | |
| SCHEMBL25391257 | 0.86 | TSHR (0.40) | PTPN1ACP1CDC25BSIRT2CETP | |
| SCHEMBL25391937 | 0.86 | TSHR (0.40) | PTPN1ACP1CDC25BSIRT2CETP | |
| SCHEMBL25392317 | 0.86 | TSHR (0.40) | PTPN1ACP1CDC25BSIRT2CETP | |
| SCHEMBL8959364 | 0.86 | TSHR (0.40) | PTPN1ACP1CDC25BSIRT2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4628836-A | USING AMINE AND SURFACTANT MIXTURE | WATERSCIENCE, INC. (US) | 1986-12-16 | — | — | US | claimed |
| US-5049311-A | Surfactants | WITCO CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0279686-A1 | Alkoxylated alkyl substituted phenol sulfonates compounds and compositions, the preparation thereof and their use in various applications | WITCO CORPORATION (US) | 1988-08-24 | — | — | EP | disclosed |
| US-4628836-A | USING AMINE AND SURFACTANT MIXTURE | WATERSCIENCE, INC. (US) | 1986-12-16 | — | — | US | disclosed |