SCHEMBL9766486

SCHEMBL9766486

CCCC(CCC)NC=O.[O]

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 5/20 0.45
ADH1A P07327 5/20 0.45
ADH1C P00326 4/20 0.45
ADH7 P40394 4/20 0.45
ADH4 P08319 2/20 0.45
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
EPHX1 P07099 2/20 0.35
SLC6A4 P31645 1/20 0.34
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8627522 0.97 ADH1B (0.46) ADH1BADH1AADH1CADH7ADH4
SCHEMBL28824011 0.88 ADH1B (0.50) ADH1BADH1AADH1CADH7ADH4
SCHEMBL270981 0.87
SCHEMBL6022099 0.84 ADH1B (0.62) ADH1BADH1AADH1CADH7ADH4
SCHEMBL10580815 0.84 ADH1B (0.62) ADH1BADH1AADH1CADH7ADH4
SCHEMBL277537 0.84 ADH1B (0.62) ADH1BADH1AADH1CADH7ADH4
SCHEMBL28217437 0.84 ADH1B (0.50) ADH1BADH1AADH1CADH7ADH4
SCHEMBL2408541 0.83
SCHEMBL2437968 0.83
SCHEMBL3530075 0.83 ADH1B (0.37) ADH1BADH1AADH1CADH7ADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075486-A Heating N-/1-propyl-n-butyl/formamide in absence of oxygen wit h alkali metal/silica gel catalyst SANOFI (FR) 1991-12-24 US claimed