SCHEMBL9766526

SCHEMBL9766526

CCC(C)CCc1ccc(SSc2ccc(CCC(C)CC)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 9/20 0.35
MAOA P21397 3/20 0.35
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNA6 Q15825 1/20 0.34
MAOB P27338 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9766497 0.89 FDFT1 (0.34) SLC6A4MAOAMAOBSLC6A2SLC6A3
SCHEMBL1979236 0.85 CHRNB2 (0.38) CHRNB2CHRNA6
SCHEMBL28383696 0.81 TAAR1 (0.48) CHRNB2CHRNA6
SCHEMBL9139045 0.79 SLC6A4 (0.46) SLC6A4MAOAMAOBSLC6A2SLC6A3
SCHEMBL27906651 0.78 GFER (0.52) MAOAMAOB
SCHEMBL11582747 0.78 ESR1 (0.52) SLC6A4SLC6A2SLC6A3
SCHEMBL22340602 0.78 TAAR1 (0.40) CHRNB2CHRNA6
SCHEMBL9766501 0.78 CHRNB2 (0.35) CHRNB2CHRNA6
SCHEMBL25824860 0.78 TAAR1 (0.45) MAOB
SCHEMBL19231716 0.78 HRH3 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034152-A Liquid crystal 4-alkylbenzenethiols, ferroelectricity CANON KABUSHIKI KAISHA (JP) 1991-07-23 US disclosed
US-4816178-A Optically active compound and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1989-03-28 US disclosed