Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260014 | 1.00 | EPHX1 (0.66) | EPHX1EPHX2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6664493 | 1.00 | EPHX1 (0.66) | EPHX1EPHX2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5510947 | 0.98 | EPHX1 (0.63) | EPHX1EPHX2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2677321 | 0.92 | EPHX2 (0.64) | EPHX1EPHX2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16439999 | 0.91 | EPHX2 (0.62) | EPHX1EPHX2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16439978 | 0.91 | EPHX2 (0.62) | EPHX1EPHX2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16440007 | 0.91 | EPHX2 (0.62) | EPHX1EPHX2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL24642929 | 0.90 | EPHX1 (0.53) | EPHX1EPHX2ALDH1A1KMT2APRMT1 | |
| SCHEMBL1288428 | 0.90 | EPHX2 (0.61) | EPHX1EPHX2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16440004 | 0.89 | EPHX2 (0.59) | EPHX1EPHX2ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003082-A | Reacting a lactam with hydrogen sulfide in the presence of an inorganic catalyst | PHILLIPS PETROLEUM COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4990628-A | Reacting lactam with hydrogen sulfide in presence of group 8 metals or compounds on alumina; support; sulfiding | PHILLIPS PETROLEUM COMPANY (US) | 1991-02-05 | — | — | US | disclosed |
| US-4956476-A | Catalytic reaction of a lactam with hydrogen sulfide to produce a thiolactam, alumina is the catalyst | PHILLIPS PETROLEUM COMPANY (US) | 1990-09-11 | — | — | US | disclosed |
| US-4145352-A | SULFACTIVE CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1979-03-20 | — | — | US | disclosed |