Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158502 | 0.97 | HSD17B10 (0.47) | HSD17B10TSHRGRM5FFAR1RARB | |
| SCHEMBL9154491 | 0.94 | GRM5 (0.44) | HSD17B10TSHRGRM5FFAR1RAB9A | |
| SCHEMBL9156046 | 0.93 | HSD17B10 (0.52) | HSD17B10TSHRGRM5FFAR1RARB | |
| SCHEMBL9158558 | 0.93 | GRM5 (0.46) | HSD17B10TSHRGRM5FFAR1RAB9A | |
| SCHEMBL9159008 | 0.90 | GRM5 (0.48) | GRM5FFAR1ACACB | |
| SCHEMBL9162555 | 0.89 | HSD17B10 (0.45) | HSD17B10TSHRGRM5FFAR1RAB9A | |
| SCHEMBL9766678 | 0.88 | HSD17B10 (0.42) | HSD17B10TSHRGRM5FFAR1RAB9A | |
| SCHEMBL9158759 | 0.87 | HSD17B10 (0.48) | HSD17B10TSHRGRM5FFAR1RAB9A | |
| SCHEMBL9766704 | 0.84 | RAB9A (0.50) | HSD17B10TSHRRARBRAB9ASMN1; SMN2 | |
| SCHEMBL9154247 | 0.83 | GRM5 (0.47) | GRM5FFAR1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |