Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | DHCR24 | Q15392 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766831 | 0.84 | TRPV1 (0.51) | TRPV1CYP3A4DHCR24ALDH1A1MAPT | |
| SCHEMBL9766734 | 0.82 | USP2 (0.59) | TRPV1DHCR24ALDH1A1MAPTALOX15 | |
| SCHEMBL665862 | 0.74 | TRPV1 (0.78) | TRPV1CYP3A4DHCR24ALDH1A1MAPT | |
| SCHEMBL6900716 | 0.74 | TRPV1 (0.78) | TRPV1CYP3A4DHCR24ALDH1A1MAPT | |
| SCHEMBL10149106 | 0.74 | TRPV1 (0.78) | TRPV1CYP3A4DHCR24ALDH1A1MAPT | |
| SCHEMBL1703700 | 0.74 | TRPV1 (0.78) | TRPV1CYP3A4DHCR24ALDH1A1MAPT | |
| SCHEMBL10000314 | 0.74 | TRPV1 (0.78) | TRPV1CYP3A4DHCR24ALDH1A1MAPT | |
| SCHEMBL21748185 | 0.74 | TRPV1 (0.78) | TRPV1CYP3A4DHCR24ALDH1A1MAPT | |
| SCHEMBL22150349 | 0.74 | TRPV1 (0.78) | TRPV1CYP3A4DHCR24ALDH1A1MAPT | |
| SCHEMBL14419156 | 0.74 | TRPV1 (0.78) | TRPV1CYP3A4DHCR24ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023250-A | Anticholesterol agents | SMITHKLINE BEECHAM CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |