Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HMGCR | P04035 | 2/20 | 0.52 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.41 |
| ▸ | EBP | Q15125 | 5/20 | 0.41 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | OSBP | P22059 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430174 | 0.85 | USP2 (0.66) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9766763 | 0.84 | HMGCR (0.73) | HMGCREBP | |
| SCHEMBL9766767 | 0.84 | HMGCR (0.73) | HMGCREBP | |
| SCHEMBL29359317 | 0.83 | USP2 (0.62) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9766781 | 0.82 | TRPV1 (0.49) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9464748 | 0.80 | USP2 (0.65) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11490959 | 0.80 | USP2 (0.65) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9464083 | 0.80 | USP2 (0.65) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9464105 | 0.80 | USP2 (0.62) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11412547 | 0.79 | USP2 (0.63) | USP2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023250-A | Anticholesterol agents | SMITHKLINE BEECHAM CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |