Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GNRHR | P30968 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589089 | 0.91 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL9402381 | 0.86 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4EGNRHRLMNA | |
| SCHEMBL9767534 | 0.81 | MEN1 (0.45) | ALDH1A1SMN1; SMN2KDM4EMEN1TP53 | |
| SCHEMBL9402501 | 0.80 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL9402283 | 0.80 | KMT2A (0.55) | ALDH1A1SMN1; SMN2GNRHRLMNAMEN1 | |
| SCHEMBL9402213 | 0.79 | KDM4E (0.63) | ALDH1A1SMN1; SMN2KDM4EGNRHRLMNA | |
| SCHEMBL7412061 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNA | |
| SCHEMBL9402388 | 0.74 | ALDH1A1 (0.56) | ALDH1A1LMNATP53MAPTSLC5A1 | |
| SCHEMBL9402270 | 0.74 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9402397 | 0.74 | ALDH1A1 (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045540-A | Amide or urea compounds containing imidazole groups | WARNER-LAMBERT CO. (US) | 1991-09-03 | — | — | US | disclosed |