Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 8/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10812533 | 0.99 | ALDH1A1 (0.56) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 | |
| SCHEMBL10724630 | 0.99 | ALDH1A1 (0.56) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 | |
| Ethylenediamine SCHEMBL10816953 | 0.96 | ALDH1A1 (0.53) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 | |
| SCHEMBL10814770 | 0.95 | ALDH1A1 (0.55) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 | |
| SCHEMBL11210390 | 0.95 | ALDH1A1 (0.55) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 | |
| Monoethanolamine SCHEMBL10987346 | 0.94 | ALDH1A1 (0.51) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 | |
| Diethanolamine SCHEMBL10813879 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 | |
| SCHEMBL10644691 | 0.90 | KDM4E (0.47) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 | |
| SCHEMBL9352330 | 0.89 | FEN1 (0.51) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 | |
| SCHEMBL9348282 | 0.88 | FEN1 (0.50) | ALDH1A1KDM4ECYP2C19HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640753-A | Method of electrocoating metallic surfaces | CIBA-GEIGY CORPORATION (US) | 1987-02-03 | — | — | US | claimed |
| EP-0092786-B1 | 1,8-NAPHTHYRIDINE AND 1,5,8-AZANAPHTHYRIDINE DERIVATIVES | SCHERING CORPORATION (US) | 1987-01-07 | — | — | EP | claimed |
| US-4452800-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIANAPHYLACTIC AGENTS | SCHERING CORPORATION (US) | 1984-06-05 | — | — | US | claimed |
| EP-0092786-A2 | 1,8-Naphthyridine and 1,5,8-azanaphthyridine derivatives | SCHERING CORPORATION (US) | 1983-11-02 | — | — | EP | claimed |
| US-5011860-A | Aryl-substituted naphthyridine and pyridopyrazine derivatives and their use in treating hyperproliferative skin diseases | SCHERING CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0228416-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AZANAPHTHALENES | SCHERING CORPORATION (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4882332-A | Immune suppression method employing arly-substituted naphthyridine and pyridopyrazine derivatives | SCHERING CORPORATION (US) | 1989-11-21 | — | — | US | disclosed |
| US-4866061-A | TREATMENT OF ALLERGIC REACTIONS, ULCERS, INFLAMMATION | SCHERING CORPORATION (US) | 1989-09-12 | — | — | US | disclosed |
| US-4760073-A | Aryl-substituted naphthyridine and pyridopyrazine derivatives, useful as anti-allergic agents | SCHERING CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0241291-A2 | Aryl-substituted naphthyridine and pyridopyrazine derivatives | SCHERING CORPORATION (US) | 1987-10-14 | — | — | EP | disclosed |
| EP-0228416-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AZANAPHTHALENES. | SCHERING CORP (US) | 1987-07-15 | — | — | EP | disclosed |
| EP-0092786-B1 | 1,8-NAPHTHYRIDINE AND 1,5,8-AZANAPHTHYRIDINE DERIVATIVES | SCHERING CORPORATION (US) | 1987-01-07 | — | — | EP | disclosed |
| WO-1986007537-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING AZANAPHTHALENES | SCHERING CORPORATION (US) | 1986-12-31 | — | — | WO | disclosed |
| US-4628055-A | ASTHMA, BRONCHITIS, 1,5,8-AZANAPHTHYRIDINES | SCHERING CORPORATION (US) | 1986-12-09 | — | — | US | disclosed |
| US-4551463-A | ANTIULCER | SCHERING CORPORATION (US) | 1985-11-05 | — | — | US | disclosed |
| US-4492702-A | ATIALLERGENS, LUNG DISEASES | SCHERING CORPORATION (US) | 1985-01-08 | — | — | US | disclosed |
| US-4452800-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIANAPHYLACTIC AGENTS | SCHERING CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |
| US-4452800-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIANAPHYLACTIC AGENTS | SCHERING CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |
| US-4452800-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIANAPHYLACTIC AGENTS | SCHERING CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0092786-A2 | 1,8-Naphthyridine and 1,5,8-azanaphthyridine derivatives | SCHERING CORPORATION (US) | 1983-11-02 | — | — | EP | disclosed |