Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922102 | 1.00 | POLB (0.40) | POLBGAAMAPK1NPSR1PDPK1 | |
| SCHEMBL12221533 | 1.00 | POLB (0.40) | POLBGAAMAPK1NPSR1PDPK1 | |
| SCHEMBL4870268 | 0.95 | POLB (0.39) | POLBGAAMAPK1NPSR1PDPK1 | |
| SCHEMBL3331155 | 0.95 | POLB (0.41) | POLBGAAMAPK1NPSR1PDPK1 | |
| SCHEMBL2744122 | 0.95 | POLB (0.41) | POLBGAAMAPK1NPSR1PDPK1 | |
| SCHEMBL4873069 | 0.95 | POLB (0.39) | POLBGAAMAPK1NPSR1PDPK1 | |
| SCHEMBL8457514 | 0.95 | POLB (0.41) | POLBGAAMAPK1NPSR1PDPK1 | |
| SCHEMBL7751731 | 0.95 | POLB (0.41) | POLBGAAMAPK1NPSR1PDPK1 | |
| SCHEMBL4870229 | 0.93 | POLB (0.38) | POLBGAAMAPK1NPSR1PDPK1 | |
| SCHEMBL7911469 | 0.93 | POLB (0.40) | POLBGAAMAPK1NPSR1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026898-A | Cell process controllers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-25 | — | — | US | disclosed |
| US-4924023-A | MEDICINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4873355-A | Process for regioselectively preparing phosphorylated inositols and other cyclitols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-10 | — | — | US | disclosed |