Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GJB2 | P29033 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331155 | 0.96 | POLB (0.41) | POLBGAAMAPK1NPSR1SLC6A2 | |
| SCHEMBL8457514 | 0.96 | POLB (0.41) | POLBGAAMAPK1NPSR1SLC6A2 | |
| SCHEMBL2744122 | 0.96 | POLB (0.41) | POLBGAAMAPK1NPSR1SLC6A2 | |
| SCHEMBL7751731 | 0.96 | POLB (0.41) | POLBGAAMAPK1NPSR1SLC6A2 | |
| SCHEMBL4873069 | 0.94 | POLB (0.39) | POLBGAAMAPK1NPSR1SLC6A2 | |
| SCHEMBL4870268 | 0.94 | POLB (0.39) | POLBGAAMAPK1NPSR1SLC6A2 | |
| SCHEMBL9456053 | 0.94 | POLB (0.39) | POLBGAAMAPK1NPSR1SLC6A2 | |
| SCHEMBL10670602 | 0.94 | POLB (0.39) | POLBGAAMAPK1NPSR1SLC6A2 | |
| SCHEMBL9767683 | 0.93 | POLB (0.40) | POLBGAAMAPK1NPSR1SLC6A2 | |
| SCHEMBL7922102 | 0.93 | POLB (0.40) | POLBGAAMAPK1NPSR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7453006-B2 | Inositol derivatives for increasing chloride secretion and inhibiting inflammation | INOLOGIC, INC. (US) | 2008-11-18 | — | — | US | disclosed |
| EP-1345950-A4 | INOSITOL DERIVATIVES FOR INCREASING CHLORIDE SECRETION AND INHIBITING INFLAMMATION | INOLOGIC INC (US) | 2005-04-27 | — | — | EP | disclosed |
| US-20040147487-A1 | Inositol derivatives for increasing chloride secretion and inhibiting inflammation | INOLOGIC, INC. | 2004-07-29 | — | — | US | disclosed |
| EP-1345950-A2 | INOSITOL DERIVATIVES FOR INCREASING CHLORIDE SECRETION AND INHIBITING INFLAMMATION | Inologic, Inc. (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002041831-A2 | INOSITOL DERIVATIVES FOR INCREASING CHLORIDE SECRETION AND INHIBITING INFLAMMATION | INOLOGIC, INC. (US) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147487-A1 | Inositol derivatives for increasing chloride secretion and inhibiting inflammation | PPIP5K2, ITPR2, ITPR3 | POLB 4554/4885GAA 4181/4885MAPK1 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.