Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | MEN1 | O00255 | 6/20 | 0.79 |
| ▸ | NPC1 | O15118 | 4/20 | 0.79 |
| ▸ | RAB9A | P51151 | 4/20 | 0.79 |
| ▸ | TP53 | P04637 | 3/20 | 0.79 |
| ▸ | MDM4 | O15151 | 1/20 | 0.77 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | AHR | P35869 | 1/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.68 |
| ▸ | PHGDH | O43175 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523681 | 0.89 | NPC1 (1.00) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL21620277 | 0.87 | POLB (0.74) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL19491391 | 0.87 | KMT2A (0.62) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL16583930 | 0.86 | DHODH (0.73) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL6059859 | 0.84 | KMT2A (0.64) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL11826793 | 0.84 | PDCD1 (0.72) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL27447692 | 0.84 | NPC1 (0.76) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL28348690 | 0.84 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL16583576 | 0.83 | NPC1 (0.62) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL21652249 | 0.83 | RAB9A (0.62) | KMT2AMEN1NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066776-A | From dihaloaromatic compound, in situ generation of alkali sulfides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-19 | — | — | US | disclosed |
| EP-0414079-A2 | Process of preparation of polyarylene sulfides | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |