⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115528 | 0.62 | — | — | |
| SCHEMBL858847 | 0.59 | — | — | |
| SCHEMBL305773 | 0.58 | — | — | |
| SCHEMBL976956 | 0.56 | — | — | |
| SCHEMBL973964 | 0.56 | — | — | |
| SCHEMBL532922 | 0.56 | — | — | |
| SCHEMBL8374076 | 0.55 | DYRK1A (0.39) | — | |
| SCHEMBL4068982 | 0.55 | — | — | |
| SCHEMBL130376 | 0.53 | — | — | |
| SCHEMBL6842125 | 0.52 | DYRK1A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115997033-A | Catalytic control sequencing by synthetic generation of traceless DNA | 伊鲁米纳公司 | 2023-04-21 | — | — | CN | disclosed |
| EP-2235016-B1 | AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2013-09-18 | — | — | EP | disclosed |
| US-8394820-B2 | N-azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2013-03-12 | — | — | US | disclosed |
| US-20110009444-A1 | N-AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-13 | — | — | US | disclosed |