Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767905 | 0.80 | NR1H4 (0.42) | NR1H4EPHX2CYP3A4TSHRNPC1 | |
| SCHEMBL7713647 | 0.80 | VCAM1 (0.46) | CYP3A4TSHRALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL9767939 | 0.75 | CYP3A4 (0.41) | NR1H4EPHX2CYP3A4TSHRHTR2A | |
| SCHEMBL15057213 | 0.71 | SLC6A4 (0.42) | NR1H4EPHX2CYP3A4TSHRNPC1 | |
| SCHEMBL27831631 | 0.71 | NR1H4 (0.39) | NR1H4EPHX2CYP3A4TSHRNPC1 | |
| SCHEMBL282088 | 0.69 | CYP3A4 (0.52) | NR1H4EPHX2CYP3A4TSHRNPC1 | |
| SCHEMBL1750351 | 0.68 | SMN1; SMN2 (0.48) | CYP3A4ALDH1A1RECQLCYP2C19MEN1 | |
| SCHEMBL2814842 | 0.68 | CYP3A4 (0.43) | NR1H4EPHX2CYP3A4TSHRHPGD | |
| SCHEMBL10583482 | 0.68 | EPHX2 (0.42) | NR1H4EPHX2CYP3A4TSHRNPC1 | |
| SCHEMBL5040154 | 0.68 | CYP3A4 (0.46) | CYP3A4TSHRHTR2ASLC6A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013354-A | Tetrahydrophthalimido group, herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |