SCHEMBL9767863

SCHEMBL9767863

COc1cc(OC)nc(Oc2ccccc2C=NOCC=Cc2cccc(Cl)c2)n1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
NFE2L2 Q16236 3/20 0.41
NPSR1 Q6W5P4 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ATM Q13315 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9767855 1.00 SMN1; SMN2 (0.44) SMN1; SMN2NFE2L2NPSR1CYP1A2CYP2C9
SCHEMBL9781812 0.90 SMN1; SMN2 (0.48) SMN1; SMN2NFE2L2ALDH1A1
SCHEMBL9781799 0.90 SMN1; SMN2 (0.48) SMN1; SMN2NFE2L2ALDH1A1
SCHEMBL9767562 0.89 SMN1; SMN2 (0.44) SMN1; SMN2NPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL9767557 0.89 SMN1; SMN2 (0.44) SMN1; SMN2NPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL9767532 0.77 MAPT (0.51) SMN1; SMN2NPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL9767530 0.77 MAPT (0.51) SMN1; SMN2NPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL9767524 0.75 ALDH1A1 (0.48) SMN1; SMN2NPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL9767528 0.75 ALDH1A1 (0.48) SMN1; SMN2NPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL9767810 0.75 SMN1; SMN2 (0.49) SMN1; SMN2NPSR1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4986846-A PRE-AND POSTEMERGENCE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-01-22 US disclosed