SCHEMBL9767979

SCHEMBL9767979

COC(=O)C(Cc1ccccc1Cl)C(=O)OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
NPC1 O15118 3/20 0.50
HTT P42858 2/20 0.49
RAB9A P51151 3/20 0.47
PPARG P37231 2/20 0.47
PPARA Q07869 2/20 0.47
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PPARD Q03181 1/20 0.43
EPHX2 P34913 1/20 0.42
GAA P10253 1/20 0.42
MDM2 Q00987 1/20 0.42
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3796731 0.92 ALDH1A1 (0.49) ALDH1A1NPC1HTTRAB9APPARG
SCHEMBL2673394 0.85 ALDH1A1 (0.50) ALDH1A1NPC1PPARGPPARAMAPT
SCHEMBL3537302 0.85 ALDH1A1 (0.51) ALDH1A1NPC1HTTRAB9APPARG
SCHEMBL4595262 0.83 ALDH1A1 (0.50) ALDH1A1NPC1HTTRAB9APPARG
SCHEMBL9767859 0.83 SLC6A2 (0.51) ALDH1A1NPC1HTTRAB9AMAPT
SCHEMBL2153012 0.83 ALDH1A1 (0.50) ALDH1A1NPC1HTTRAB9APPARG
SCHEMBL1066220 0.83 ALDH1A1 (0.50) ALDH1A1NPC1HTTRAB9APPARG
SCHEMBL11444938 0.83 ALDH1A1 (0.50) ALDH1A1NPC1HTTRAB9APPARG
Hydrochloric Acid SCHEMBL3986125 0.82 ALDH1A1 (0.49) ALDH1A1NPC1HTTRAB9APPARG
Hydrochloric Acid SCHEMBL1066219 0.82 ALDH1A1 (0.49) ALDH1A1NPC1HTTRAB9APPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5013354-A Tetrahydrophthalimido group, herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-05-07 US disclosed
EP-0300398-A2 3-Phenylpropionic acid derivatives BASF Aktiengesellschaft (DE) 1989-01-25 EP disclosed