SCHEMBL9768014

SCHEMBL9768014

Oc1ccc(C(O)CNCCc2ccccc2)cc1O

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 17/20 0.69
ADRB3 P13945 1/20 0.67
ADRA1D P25100 1/20 0.67
ADRB1 P08588 5/20 0.65
DRD2 P14416 2/20 0.65
DRD1 P21728 2/20 0.65
DRD4 P21917 2/20 0.65
DRD3 P35462 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10908406 0.85 ADRB2 (0.64) ADRB2ADRB3ADRA1DADRB1DRD2
SCHEMBL30892159 0.85 ADRB3 (0.64) ADRB2ADRB3ADRA1DADRB1DRD2
SCHEMBL22551319 0.85 ADRB3 (0.64) ADRB2ADRB3ADRA1DADRB1DRD2
SCHEMBL31530707 0.84 ADRB2 (0.68) ADRB2ADRB3ADRA1DADRB1DRD2
SCHEMBL31530706 0.84 ADRB2 (0.68) ADRB2ADRB3ADRA1DADRB1DRD2
Hydrochloric Acid SCHEMBL27537984 0.84 ADRB3 (0.63) ADRB2ADRB3ADRA1DADRB1DRD2
SCHEMBL10477708 0.83 ADRB2 (0.80) ADRB2ADRB3ADRA1DADRB1DRD2
SCHEMBL10477723 0.83 ADRB2 (0.80) ADRB2ADRB3ADRA1DADRB1DRD2
SCHEMBL10720145 0.82 ADRB2 (0.77) ADRB2ADRB3ADRA1D
SCHEMBL27935617 0.82 ADRB2 (0.78) ADRB2ADRB3ADRA1DADRB1DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047592-A Selective hydrogenolysis process ETHYL CORPORATION (US) 1991-09-10 US disclosed
US-3952021-A α-(3,4-Dimethoxyphenethylaminomethyl)-3,4 or 3,5-dihydroxybenzylalcohols and salts thereof TANABE SEIYAKU CO., LTD. (JA) 1976-04-20 US disclosed