Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414869 | 0.95 | PTAFR (0.51) | PTAFRLMNACA1CA2CA4 | |
| SCHEMBL318046 | 0.79 | GID4 (0.43) | KMT2AALDH1A1TSHR | |
| SCHEMBL9719028 | 0.79 | PTAFR (0.55) | PTAFRLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9719064 | 0.79 | PTAFR (0.55) | PTAFRLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9719047 | 0.79 | PTAFR (0.55) | PTAFRLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11844345 | 0.78 | PDE4A (0.51) | LMNAKMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL4129415 | 0.76 | PDE4A (0.50) | LMNAKMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL28455534 | 0.76 | PDE4A (0.53) | PTAFRLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28890937 | 0.75 | PDE4B (0.43) | LMNACA1CA2CA4CA6 | |
| SCHEMBL10109186 | 0.75 | MAPK1 (0.45) | LMNACA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047420-A | Platelet activating factor | MERCK & CO., INC. (US) | 1991-09-10 | — | — | US | disclosed |