Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503706 | 0.82 | HPGD (0.62) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL5932634 | 0.82 | HPGD (0.68) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL18179454 | 0.81 | KMT2A (0.52) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL12961212 | 0.80 | ALDH1A1 (0.37) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9432569 | 0.80 | HPGD (0.65) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 | |
| Bromide SCHEMBL10777716 | 0.80 | HPGD (0.65) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL18306239 | 0.78 | HPGD (0.62) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL11964825 | 0.77 | NPC1 (0.53) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL16221574 | 0.77 | DPP4 (0.45) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL17414793 | 0.77 | HPGD (0.56) | HPGDKMT2ASMN1; SMN2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047592-A | Selective hydrogenolysis process | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |