Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CTSC | P53634 | 1/20 | 0.55 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313727 | 1.00 | RECQL (0.62) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL7313737 | 1.00 | RECQL (0.62) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL20489442 | 0.99 | RECQL (0.61) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL20489447 | 0.99 | RECQL (0.61) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL20489444 | 0.99 | RECQL (0.61) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL28258588 | 0.93 | RECQL (0.63) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL28080635 | 0.87 | CYP3A4 (0.47) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL30524836 | 0.86 | BRAF (0.48) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL24057819 | 0.85 | LMNA (0.60) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL7305357 | 0.85 | LMNA (0.60) | RECQLCYP3A4CYP2D6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000905-A1 | SUBSTITUTED 2-CARBOXAMIDE CYCLOAMINO UREAS | NOVARTIS AG (CH) | 2011-01-06 | — | — | WO | disclosed |