Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | XBP1 | P17861 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672474 | 0.86 | RAB9A (0.74) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 | |
| SCHEMBL10788065 | 0.83 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 | |
| SCHEMBL4670658 | 0.83 | RAB9A (0.70) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 | |
| SCHEMBL4648855 | 0.83 | RAB9A (0.70) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 | |
| SCHEMBL24303253 | 0.83 | NPC1 (0.70) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 | |
| SCHEMBL1461789 | 0.82 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 | |
| SCHEMBL24091280 | 0.81 | CA1 (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 | |
| SCHEMBL31735886 | 0.81 | RAB9A (0.72) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 | |
| SCHEMBL11135676 | 0.80 | CA12 (0.78) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 | |
| SCHEMBL8163897 | 0.80 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1ALDH1A1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003049-A | Fiber-Reactive Dyes for Hydroxy Textiles | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-26 | — | — | US | disclosed |
| US-4677199-A | Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-30 | — | — | US | disclosed |
| EP-0119441-B1 | REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS | BASF Aktiengesellschaft (DE) | 1987-02-25 | — | — | EP | disclosed |
| EP-0126265-B1 | REACTIVE DYES | BASF Aktiengesellschaft (DE) | 1986-10-29 | — | — | EP | disclosed |
| EP-0126265-A1 | Reactive dyes | BASF Aktiengesellschaft (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0119441-A2 | Reactive dyes with substituted 4-fluoropyridaz-6-one groups | BASF Aktiengesellschaft (DE) | 1984-09-26 | — | — | EP | disclosed |