Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768410 | 0.92 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53HIF1ASMN1; SMN2 | |
| SCHEMBL10669694 | 0.79 | CA12 (0.43) | CA12CA9CA1MAOAMAOB | |
| SCHEMBL10670024 | 0.78 | KDM4E (0.51) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL8584061 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TSHRTP53HIF1ASMN1; SMN2 | |
| SCHEMBL9781442 | 0.76 | MEN1 (0.35) | ALDH1A1HIF1AKDM4EHPGDMAPT | |
| SCHEMBL10668886 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TSHRTP53HIF1ASMN1; SMN2 | |
| SCHEMBL10572539 | 0.74 | KDM4E (0.58) | ALDH1A1TSHRTP53HIF1ASMN1; SMN2 | |
| SCHEMBL19183532 | 0.74 | ALDH1A1 (0.62) | ALDH1A1TSHRTP53SMN1; SMN2KDM4E | |
| SCHEMBL9781440 | 0.74 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL9781415 | 0.74 | KDM4E (0.55) | ALDH1A1TSHRTP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |