Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353046 | 0.81 | MEN1 (0.36) | MEN1ALDH1A1GLAMAPTHPGD | |
| SCHEMBL1731502 | 0.81 | MEN1 (0.36) | MEN1ALDH1A1GLAMAPTHPGD | |
| SCHEMBL17789931 | 0.78 | MEN1 (0.34) | MEN1ALDH1A1GLAMAPTHPGD | |
| SCHEMBL5114694 | 0.77 | MEN1 (0.42) | MEN1ALDH1A1GLAMAPTHPGD | |
| SCHEMBL9223316 | 0.72 | DAO (0.45) | MEN1ALDH1A1GLAMAPTHPGD | |
| SCHEMBL8532981 | 0.70 | ALOX5 (0.39) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL2229904 | 0.69 | — | — | |
| SCHEMBL21210990 | 0.69 | MEN1 (0.36) | MEN1ALDH1A1GLAMAPTHPGD | |
| SCHEMBL2069257 | 0.69 | CYP2C9 (0.50) | MEN1ALDH1A1GLAMAPTHPGD | |
| SCHEMBL9768556 | 0.69 | TSHR (0.34) | MEN1ALDH1A1GLAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011918-A | Siloxane Derivatives Are Useful In Glass Fiber Sizing Compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4929670-A | GLASS SIZING COMPOSITIONS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4839449-A | SIZING COMPOSITION FOR GLASS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0314063-A2 | Polysaccharides containing aromatic aldehydes and their derivatization via amine-aldehyde interactions | National Starch and Chemical Corporation (US) | 1989-05-03 | — | — | EP | disclosed |