Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 10/20 | 0.46 |
| ▸ | CNR1 | P21554 | 9/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318839 | 0.82 | CNR2 (0.46) | CDC25BCNR2CNR1ALDH1A1HTT | |
| SCHEMBL5911604 | 0.81 | CDC25B (0.61) | CDC25BNR4A1NR4A2NR4A3CNR2 | |
| SCHEMBL4068640 | 0.81 | BCL2 (0.44) | CDC25BNR4A1NR4A2NR4A3CNR2 | |
| SCHEMBL4899928 | 0.80 | HSD17B10 (0.55) | CDC25BNR4A1NR4A2NR4A3MAPT | |
| SCHEMBL2319104 | 0.79 | CES2 (0.49) | CNR2CNR1MAPTMEN1KMT2A | |
| SCHEMBL11383181 | 0.77 | CDC25B (0.56) | CDC25BNR4A1NR4A2NR4A3CNR2 | |
| SCHEMBL6238903 | 0.77 | BCL2L1 (0.55) | CDC25BNR4A1NR4A2NR4A3CNR2 | |
| SCHEMBL31338901 | 0.77 | CDC25B (0.54) | CDC25BNR4A1NR4A2NR4A3CNR2 | |
| SCHEMBL244802 | 0.76 | CDC25B (0.80) | CDC25BNR4A1NR4A2NR4A3CNR2 | |
| SCHEMBL29414437 | 0.76 | CDC25B (0.80) | CDC25BNR4A1NR4A2NR4A3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002942-A | Calcium channel blockers for cardiovascular disorders | SANKYO COMPANY, LIMITED (JP) | 1991-03-26 | — | — | US | disclosed |