Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18067908 | 0.83 | ALDH1A1 (0.38) | ALDH1A1LMNARECQL | |
| SCHEMBL19513763 | 0.81 | ESR1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL17192984 | 0.81 | ESR1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL16405008 | 0.81 | ESR1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL3503770 | 0.80 | MAPT (0.42) | POLBALDH1A1RECQL | |
| SCHEMBL18067900 | 0.79 | ALDH1A1 (0.42) | TDP1ALDH1A1 | |
| SCHEMBL18067920 | 0.78 | POLB (0.38) | POLBTDP1 | |
| SCHEMBL18067914 | 0.77 | POLB (0.37) | POLBTDP1ALDH1A1LMNAPRNP | |
| SCHEMBL45854 | 0.76 | — | — | |
| SCHEMBL16563787 | 0.76 | TAAR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |