Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | GRK2 | P25098 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769012 | 1.00 | KMT2A (0.63) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| Water SCHEMBL9768838 | 0.98 | KMT2A (0.61) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL9768940 | 0.98 | KMT2A (0.61) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL9768938 | 0.98 | KMT2A (0.61) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| Water SCHEMBL9768836 | 0.98 | KMT2A (0.61) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL10624649 | 0.83 | MEN1 (0.61) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL10624644 | 0.83 | MEN1 (0.61) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL10811923 | 0.83 | CYP1A2 (0.62) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL4115183 | 0.82 | MEN1 (0.77) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4115180 | 0.82 | MEN1 (0.77) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023334-A | Anthelmintic pyridinyl acylhydrazones | THE UPJOHN COMPANY (US) | 1991-06-11 | — | — | US | claimed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | claimed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | claimed |
| US-5023334-A | Anthelmintic pyridinyl acylhydrazones | THE UPJOHN COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| US-5011932-A | Anthelmintic pyridinyl acylhydrazones derivatives | UPJOHN COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | disclosed |