Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | G6PD | P11413 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4115180 | 1.00 | MEN1 (0.77) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| SCHEMBL549490 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| SCHEMBL78287 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| SCHEMBL31588094 | 0.87 | MEN1 (0.77) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| SCHEMBL333482 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| SCHEMBL9067815 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| Phenylsemicarbazone SCHEMBL11882629 | 0.83 | MEN1 (0.71) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| SCHEMBL13496984 | 0.83 | MEN1 (0.71) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| SCHEMBL28645597 | 0.83 | MEN1 (0.71) | MEN1KMT2ACYP1A2RAB9ANPC1 | |
| SCHEMBL20053530 | 0.83 | MEN1 (0.71) | MEN1KMT2ACYP1A2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |
| EP-1776334-B1 | USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES | FIRMENICH & CIE (CH) | 2009-10-14 | — | — | EP | disclosed |
| US-20090062358-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONISTS | CANO IVAN COLLADO | 2009-03-05 | — | — | US | disclosed |
| EP-1335908-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONISTS | LILLY CO ELI (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7304062-B2 | Peroxisome proliferator activated receptor alpha agonists | ELI LILLY AND COMPANY (US) | 2007-12-04 | — | — | US | disclosed |
| US-20070141011-A1 | USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES | UNIVERSITE LOUIS PASTEUR (FR) | 2007-06-21 | — | — | US | disclosed |
| EP-1776334-A1 | USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES | FIRMENICH SA (CH) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006016248-A1 | USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES | FIRMENICH SA (CH) | 2006-02-16 | — | — | WO | disclosed |
| US-20040102500-A1 | Peroxisome proliferator activated receptor alpha agonists | CANO IVAN COLLADO (ES) | 2004-05-27 | — | — | US | disclosed |
| EP-1335908-A2 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONISTS | ELI LILLY AND COMPANY (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1181284-B1 | DIPHENYL-1,2,3-THIADIAZOL-3-OXIDES, COMPOSITIONS AND METHODS OF USE | MERCK FROSST CANADA INC (CA) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002038553-A2 | TRIAZOLE DERIVATIVES AND THEIR USE AS PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONISTS | ELI LILLY AND COMPANY (US) | 2002-05-16 | — | — | WO | disclosed |
| EP-1181284-A1 | DIPHENYL-1,2,3-THIADIAZOL-3-OXIDES, COMPOSITIONS AND METHODS OF USE | MERCK FROSST CANADA INC. (CA) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000068215-A1 | DIPHENYL-1,2,3-THIADIAZOL-3-OXIDES, COMPOSITIONS AND METHODS OF USE | MERCK FROSST CANADA & CO. (CA) | 2000-11-16 | — | — | WO | disclosed |
| EP-0923539-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998003473-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102500-A1 | Peroxisome proliferator activated receptor alpha agonists | PPARG, PPARA, PPARD | MEN1 4880/4885KMT2A 3230/4885CYP1A2 430/4885 |
| US-20090062358-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONISTS | PPARG, PPARA, PPARD | MEN1 4873/4885KMT2A 3695/4885CYP1A2 452/4885 |
| US-20070141011-A1 | USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES | TRPA1, HCN1, HCN4 | MEN1 1479/4885KMT2A 3021/4885CYP1A2 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.