Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Geraniol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.83 |
| ▸ | MEN1 | O00255 | 3/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 2/20 | 0.58 |
| ▸ | FNTB | P49356 | 2/20 | 0.58 |
| ▸ | SQLE | Q14534 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Geraniol SCHEMBL20481434 | 1.00 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Nerol SCHEMBL28146868 | 1.00 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geraniol SCHEMBL57142 | 1.00 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geraniol SCHEMBL3664268 | 1.00 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Farnesol SCHEMBL509427 | 0.98 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Farnesol SCHEMBL29087994 | 0.98 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geranylgeraniol SCHEMBL1573864 | 0.98 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Nerol SCHEMBL28538301 | 0.96 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geraniol SCHEMBL27824090 | 0.96 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geraniol SCHEMBL5576765 | 0.93 | KMT2A (0.86) | KMT2AALOX15MEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011688-A | Analgesic, antihistamine, diuretic and flavorings | CALAM AND ASSOCIATES, INC. | 1991-04-30 | — | — | US | disclosed |