Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Geraniol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.83 |
| ▸ | MEN1 | O00255 | 3/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 2/20 | 0.58 |
| ▸ | FNTB | P49356 | 2/20 | 0.58 |
| ▸ | SQLE | Q14534 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Geraniol SCHEMBL20481434 | 1.00 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Nerol SCHEMBL28146868 | 1.00 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geraniol SCHEMBL9769106 | 1.00 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geraniol SCHEMBL3664268 | 1.00 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Farnesol SCHEMBL509427 | 0.98 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Farnesol SCHEMBL29087994 | 0.98 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geranylgeraniol SCHEMBL1573864 | 0.98 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Nerol SCHEMBL28538301 | 0.96 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geraniol SCHEMBL27824090 | 0.96 | KMT2A (0.83) | KMT2AALOX15MEN1CYP3A4MAPT | |
| Geraniol SCHEMBL5576765 | 0.93 | KMT2A (0.86) | KMT2AALOX15MEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 981 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590265-B2 | 1-norbornan-2-ylpropan-2-one as a fragrance | SYMRISE AG (DE) | 2026-03-31 | — | — | US | claimed |
| US-12568998-B2 | Flavouring composition with balanced taste profile | SYMRISE AG (DE) | 2026-03-10 | — | — | US | claimed |
| EP-4519402-B1 | 1-NORBORNAN-2-YLPROPAN-2-ONE AS A FRAGRANCE | SYMRISE AG (DE) | 2025-12-10 | — | — | EP | claimed |
| WO-2025202181-A1 | TERPENOID COMPOSITIONS AND BLENDS THEREOF | EVODIABIO APS (DK) | 2025-10-02 | — | — | WO | claimed |
| EP-4444108-B1 | ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT | SYMRISE AG (DE) | 2025-09-10 | — | — | EP | claimed |
| US-20250257283-A1 | 1-NORBORNAN-2-YLPROPAN-2-ONE AS A FRAGRANCE | SYMRISE AG (DE) | 2025-08-14 | — | — | US | claimed |
| CN-119924491-A | Flavoring composition with balanced taste characteristics | 西姆莱斯有限公司 | 2025-05-06 | — | — | CN | claimed |
| EP-4519402-A1 | 1-NORBORNAN-2-YLPROPAN-2-ONE AS A FRAGRANCE | Symrise AG (DE) | 2025-03-12 | — | — | EP | claimed |
| CN-119424273-A | Skin care composition, preparation method and application thereof | 稳健医疗用品股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| US-20250040580-A1 | ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT | SYMRISE AG (DE) | 2025-02-06 | — | — | US | claimed |
| CN-1625595-A | Essential oil containing citronellol and rose oxide extracted from gardenia jasminoides ellis and extraction method thereof | COCENCIL SCIENT IND RES (IN) | 2005-06-08 | — | — | CN | claimed |
| US-6831214-B2 | Crop burning; weed control; cloning | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2004-12-14 | — | — | US | claimed |
| CN-1101227-C | Silicone compositions | PROCTER & GAMBLE (US) | 2003-02-12 | — | — | CN | claimed |
| CN-1090918-C | Silicone compositions | P & G CO (US) | 2002-09-18 | — | — | CN | claimed |
| CN-1175278-A | Perfumed bleaching compositions | PROCTER & GAMBLE (US) | 1998-03-04 | — | — | CN | claimed |
| CN-1170431-A | Silicone compositions | PROCTER & GAMBLE (US) | 1998-01-14 | — | — | CN | claimed |
| CN-1170430-A | Silicone compositions | PROCTER & GAMBLE (US) | 1998-01-14 | — | — | CN | claimed |
| CN-1170352-A | Silicone compositions | PROCTER & GAMBLE (US) | 1998-01-14 | — | — | CN | claimed |
| CN-1170340-A | Silicone compositions | PROCTER & GAMBLE (US) | 1998-01-14 | — | — | CN | claimed |
| WO-1990008537-A1 | PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION | ABBOTT LABORATORIES (US) | 1990-08-09 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12568998-B2 | Flavouring composition with balanced taste profile | TAS2R20, TAS2R50, TAS2R40 | KMT2A 4340/4885ALOX15 2662/4885MEN1 1082/4885 |
| US-12590265-B2 | 1-norbornan-2-ylpropan-2-one as a fragrance | OR10J3, TAS2R40, TAS2R50 | KMT2A 2016/4885ALOX15 929/4885MEN1 1446/4885 |
| US-20250257283-A1 | 1-NORBORNAN-2-YLPROPAN-2-ONE AS A FRAGRANCE | FLNA, FLNB, LMAN1 | KMT2A 1558/4885ALOX15 133/4885MEN1 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.