Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.47 |
| ▸ | STK10 | O94804 | 7/20 | 0.47 |
| ▸ | SLK | Q9H2G2 | 7/20 | 0.47 |
| ▸ | WEE1 | P30291 | 7/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11756770 | 0.81 | PARP1 (0.45) | GSK3BSTK10SLKWEE1CHEK1 | |
| SCHEMBL7896263 | 0.77 | PPOX (0.46) | GSK3BSTK10SLKCHEK1GSK3A | |
| SCHEMBL11430142 | 0.77 | CYP1A2 (0.43) | GSK3BSTK10SLKWEE1CHEK1 | |
| SCHEMBL9769224 | 0.77 | TYMS (0.50) | WEE1MEN1CYP1A2PARP1KMT2A | |
| Phthalimide SCHEMBL1501259 | 0.73 | GSK3B (0.60) | GSK3BSTK10SLKCHEK1GSK3A | |
| SCHEMBL261439 | 0.73 | GSK3B (0.52) | GSK3BSTK10SLKWEE1CHEK1 | |
| SCHEMBL28151010 | 0.71 | GSK3B (0.47) | GSK3BSTK10SLKWEE1CHEK1 | |
| Benzene SCHEMBL28220879 | 0.71 | GSK3B (0.50) | GSK3BSTK10SLKWEE1CHEK1 | |
| SCHEMBL338831 | 0.70 | PARP1 (0.51) | GSK3BWEE1CHEK1GSK3APRKACA | |
| Biphenyl SCHEMBL27584116 | 0.69 | GSK3B (0.48) | GSK3BSTK10SLKPARP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053323-A | Optical information media comprising phenyl-substituted naphthalocyanines and synthesis thereof | BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA, THE | 1991-10-01 | — | — | US | disclosed |