Maleic Anhydride

Maleic Anhydride

SCHEMBL9769215

C=CC(=O)OCCCC.C=COC(C)=O.O=C1C=CC(=O)O1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.56
HPGD P15428 1/20 0.56
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 1/20 0.41
ATM Q13315 1/20 0.41
THRB P10828 4/20 0.37
HCAR2 Q8TDS4 3/20 0.37
TP53 P04637 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 1/20 0.35
APP P05067 1/20 0.34
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Anhydride SCHEMBL10477470 0.95 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4ATM
Maleic Anhydride SCHEMBL2371034 0.91 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4ATM
Maleic Anhydride SCHEMBL3392685 0.89 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM
Acrylic Acid Ethyl Ester SCHEMBL9793707 0.87 TSHR (0.36) TSHRHPGDALDH1A1CYP3A4THRB
Maleic Anhydride SCHEMBL28490508 0.87 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL10823313 0.86 TSHR (0.76) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL8356892 0.86 TSHR (0.76) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL664120 0.86 TSHR (0.76) TSHRHPGDALDH1A1CYP3A4ATM
Maleic Anhydride SCHEMBL5506367 0.85 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4ATM
Maleic Anhydride SCHEMBL11087306 0.85 TSHR (0.60) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0414353-A2 Adhesive and repulpable tape coated therewith THE KENDALL COMPANY (US) 1991-02-27 EP disclosed
US-4992501-A Repulpable tape THE KENDALL COMPANY (US) 1991-02-12 US disclosed
US-4482675-A Water-soluble, pressure-sensitive adhesive composition, and process for making same COLGATE-PALMOLIVE COMPANY (US) 1984-11-13 US disclosed