Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Anhydride SCHEMBL2371034 | 0.98 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Maleic Anhydride SCHEMBL28490508 | 0.94 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Maleic Anhydride SCHEMBL5506367 | 0.93 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Maleic Anhydride SCHEMBL11087306 | 0.93 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Maleic Anhydride SCHEMBL1427836 | 0.93 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Maleic Anhydride SCHEMBL28724985 | 0.93 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Maleic Anhydride SCHEMBL9769215 | 0.89 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Maleic Anhydride SCHEMBL21196525 | 0.89 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Styrene SCHEMBL2370337 | 0.87 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Maleic Anhydride SCHEMBL5504158 | 0.87 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084219-B1 | POLYMERIC COUPLING AGENTS | LUBRIZOL LTD (GB) | 2012-09-05 | — | — | EP | claimed |
| US-20090306252-A1 | Polymeric Coupling Agents | LUBRIZOL LIMITED (GB) | 2009-12-10 | — | — | US | claimed |
| EP-2084219-A1 | POLYMERIC COUPLING AGENTS | Lubrizol Limited (GB) | 2009-08-05 | — | — | EP | claimed |
| WO-2008049840-A1 | POLYMERIC COUPLING AGENTS | LUBRIZOL LIMITED (GB) | 2008-05-02 | — | — | WO | claimed |
| CN-117362997-B | Conductive copper bar insulation rubber coating and preparation method | 厦门爱瑞克电子有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117841483-A | Sound-absorbing and sound-insulating material and preparation method thereof | 北京哈泰克工程技术有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117362997-A | Conductive copper bar insulation rubber coating and preparation method | 厦门爱瑞克电子有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-116278268-A | VMCPP film with high gloss and superhigh moisture resistance, three-layer composite film and preparation method thereof | 黄山永新股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111978628-A | PP and PA6 blending modified composite material and preparation method thereof | 四川鑫达企业集团有限公司 | 2020-11-24 | — | — | CN | disclosed |
| EP-2158902-B1 | ION BINDING COMPOSITIONS AND THEIR USE | RELYPSA INC (US) | 2017-12-06 | — | — | EP | disclosed |
| EP-3152258-A1 | IMPACT IMPROVED FILLED POLYCARBONATE OR POLYESTER COMPOSITIONS | SABIC Global Technologies B.V. (NL) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015189753-A1 | IMPACT IMPROVED FILLED POLYCARBONATE OR POLYESTER COMPOSITIONS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2015-12-17 | — | — | WO | disclosed |
| US-20090148533-A1 | ION BINDING COMPOSITIONS | RELYPSA, INC. (US) | 2009-06-11 | — | — | US | disclosed |
| US-7429394-B2 | Ion binding compositions | RELYPSA, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| WO-2008049840-A1 | POLYMERIC COUPLING AGENTS | LUBRIZOL LIMITED (GB) | 2008-05-02 | — | — | WO | disclosed |
| US-20060024336-A1 | Core comprising a potassium binding polymer, shell component comprising a crosslinked amine functional polymer alkylated with hydrophobic agent(s); treatment of phosphate imbalance disorders, hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency | VIFOR (INTERNATIONAL) LTD. (CH) | 2006-02-02 | — | — | US | disclosed |
| US-20050220889-A1 | Ion binding compositions | SYMYX THERAPEUTICS, INC. (US) | 2005-10-06 | — | — | US | disclosed |
| US-20050220890-A1 | Ion binding compositions | SYMYX THERAPEUTICS, INC. (US) | 2005-10-06 | — | — | US | disclosed |
| CN-1213854-C | Thermoformable multilayer film for protecting a substrate and resulting article | ATOFINA (FR) | 2005-08-10 | — | — | CN | disclosed |
| CN-1321578-A | Thermoformable multilayer film for protecting a substrate and resulting article | ATOFINA (FR) | 2001-11-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050220890-A1 | Ion binding compositions | SLC10A1, SLC8B1, ATP2A3 | TSHR 3562/4885HPGD 1514/4885ALDH1A1 3384/4885 |
| US-20090148533-A1 | ION BINDING COMPOSITIONS | SLC10A1, SLC8B1, ATP2A3 | TSHR 3562/4885HPGD 1514/4885ALDH1A1 3384/4885 |
| US-20050220889-A1 | Ion binding compositions | SLC10A1, SLC8B1, ATP2A3 | TSHR 3562/4885HPGD 1514/4885ALDH1A1 3384/4885 |
| US-20060024336-A1 | Core comprising a potassium binding polymer, shell component comprising a crosslinked amine functional polymer alkylated with hydrophobic agent(s); treatment of phosphate imbalance disorders, hypertension, chronic heart failure, end stage renal disease, liver cirrhosis, chronic renal insufficiency | SLC10A1, ATP6V1B1, KCNH3 | TSHR 3303/4885HPGD 1571/4885ALDH1A1 3290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.