Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.39 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018904 | 1.00 | RAB9A (0.41) | RAB9AHCRTR2ACERENKDM4E | |
| SCHEMBL1861008 | 0.81 | TSHR (0.42) | RAB9AHCRTR2 | |
| SCHEMBL12952568 | 0.81 | RAB9A (0.64) | RAB9AHCRTR2 | |
| SCHEMBL13532420 | 0.79 | RAB9A (0.43) | RAB9AHCRTR2KDM4E | |
| SCHEMBL12133179 | 0.79 | RAB9A (0.43) | RAB9AHCRTR2KDM4E | |
| SCHEMBL8251925 | 0.78 | DPP4 (0.44) | — | |
| SCHEMBL12001763 | 0.77 | ACE (0.41) | ACERENKDM4EF2LMNA | |
| SCHEMBL12787401 | 0.77 | GAA (0.42) | RAB9AHCRTR2 | |
| SCHEMBL190173 | 0.77 | HSD17B10 (0.49) | LMNAMAPTHSD17B10 | |
| SCHEMBL12282720 | 0.77 | POLB (0.58) | RAB9AHCRTR2ACERENLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |