Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23215199 | 0.73 | EGLN2 (0.47) | EGLN2 | |
| SCHEMBL12646055 | 0.66 | HTR2A (0.40) | KMT2AALDH1A1THRBHPGD | |
| SCHEMBL13209735 | 0.65 | HPGD (0.41) | KMT2AALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL1691581 | 0.61 | MKNK1 (0.47) | ALDH1A1HPGDFYN | |
| SCHEMBL13024178 | 0.60 | IDH1 (0.62) | KMT2AALDH1A1THRBKDM4EHPGD | |
| SCHEMBL13024189 | 0.59 | HDAC4 (0.70) | KMT2AALDH1A1THRBMAPT | |
| SCHEMBL18078708 | 0.59 | ALDH1A1 (0.42) | KMT2AALDH1A1KDM4EHPGDGLA | |
| SCHEMBL8378548 | 0.59 | FYN (0.35) | KMT2AALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL26538138 | 0.58 | BAZ2B (0.41) | KMT2ATHRBKDM4EPOLBMAPT | |
| SCHEMBL19491595 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019578-A | β-adrenergic agonists | MERCK & CO., INC. (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0318092-A2 | Novel beta-adrenergic agonists | MERCK & CO. INC. (US) | 1989-05-31 | — | — | EP | disclosed |