Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL1367651 | 0.96 | — | — | |
| Acrylic Acid SCHEMBL5315493 | 0.96 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL58706 | 0.96 | — | — | |
| Acrylic Acid SCHEMBL9105078 | 0.96 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL11401396 | 0.96 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL11661859 | 0.96 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL5340041 | 0.96 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL9105158 | 0.96 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL10624484 | 0.96 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL10821154 | 0.96 | LMNA (0.91) | LMNAALOX15HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108326229-A | A kind of high intensity releasing agent and preparation method thereof | 苏州捷德瑞精密机械有限公司 | 2018-07-27 | — | — | CN | claimed |
| JP-3230009-A | — | — | None | — | — | JP | disclosed |
| CN-109650430-A | A kind of method of high content of magnesium lime stone preparation nanometer calcium carbonate | 广西华纳新材料科技有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-101679170-B | Ether compound | KAO CORP | 2013-05-22 | — | — | CN | disclosed |
| CN-102143815-A | Cover plate for perforating printed circuit board, water-soluble lubricating resin composition for use therein, and process for producing the same | SANG A FLONTEC CO LTD | 2011-08-03 | — | — | CN | disclosed |
| CN-101808709-A | Filter element and filter unit | TORAY INDUSTRIES | 2010-08-18 | — | — | CN | disclosed |
| CN-100444015-C | Liquid for electrophoretic display, display medium using the same, and display device | MITSUBISHI PENCIL CO (JP) | 2008-12-17 | — | — | CN | disclosed |
| CN-100396263-C | Auxiliary pad for mounting absorbable article | UNI CHARM CORP (JP) | 2008-06-25 | — | — | CN | disclosed |
| CN-1306923-C | Absorptive article | DAIO SEISHI KK (JP) | 2007-03-28 | — | — | CN | disclosed |
| CN-1846165-A | Liquid for electrophoretic display, display medium using the same, and display device | MITSUBISHI PENCIL CO (JP) | 2006-10-11 | — | — | CN | disclosed |
| CN-1697620-A | Method and device for manufacturing sound absorbing carpet | DAIWA KK (JP) | 2005-11-16 | — | — | CN | disclosed |
| CN-1688271-A | Auxiliary pad for mounting absorbable article | UNI CHARM CORP (JP) | 2005-10-26 | — | — | CN | disclosed |
| CN-1674843-A | Absorptive article | DAIO SEISHI KK (JP) | 2005-09-28 | — | — | CN | disclosed |
| CN-1192888-A | Infant's short pants for exercitation | UNI CHARM CORP (JP) | 1998-09-16 | — | — | CN | disclosed |
| JP-H03230009-A | FIXED TANK FOR KEROSENE HEATER | MATSUSHITA ELECTRIC IND CO LTD | 1991-10-14 | — | — | JP | disclosed |