Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 9/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243737 | 0.87 | NR4A2 (0.63) | NR4A2BRD4ALDH1A1KMT2ALMNA | |
| SCHEMBL9161064 | 0.80 | SRC (0.61) | NR4A2ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL5246371 | 0.80 | NR4A2 (0.65) | NR4A2BRD4ALDH1A1KMT2ALMNA | |
| SCHEMBL7985067 | 0.78 | NR4A2 (0.64) | NR4A2ALDH1A1 | |
| SCHEMBL19202569 | 0.78 | NR4A2 (0.63) | NR4A2BRD4ALDH1A1KMT2ALMNA | |
| SCHEMBL497718 | 0.78 | NR4A2 (0.63) | NR4A2BRD4ALDH1A1KMT2ALMNA | |
| SCHEMBL2434205 | 0.77 | NR4A2 (0.58) | NR4A2BRD4LMNAHPGDSMN1; SMN2 | |
| SCHEMBL2495561 | 0.74 | NR4A2 (0.54) | NR4A2BRD4ALDH1A1KMT2ALMNA | |
| SCHEMBL1092934 | 0.74 | NR4A2 (1.00) | NR4A2BRD4ALDH1A1KMT2ALMNA | |
| SCHEMBL31621504 | 0.74 | NR4A2 (1.00) | NR4A2BRD4ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034015-A | Fade resistant hair dyes with better coloring ability | L'OREAL (FR) | 1991-07-23 | — | — | US | claimed |
| US-5034015-A | Fade resistant hair dyes with better coloring ability | L'OREAL (FR) | 1991-07-23 | — | — | US | disclosed |
| EP-0360638-A1 | Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor | L'OREAL (FR) | 1990-03-28 | — | — | EP | disclosed |