SCHEMBL9769398

SCHEMBL9769398

O=S(=O)(c1ccc(O)c(Cl)c1)c1ccc(O)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.57
GAA P10253 4/20 0.50
ALDH1A1 P00352 1/20 0.50
PKM P14618 1/20 0.50
GFER P55789 1/20 0.47
HSD11B1 P28845 6/20 0.43
PTGS1 P23219 2/20 0.43
PTGS2 P35354 1/20 0.43
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
MAPT P10636 1/20 0.41
HSD17B3 P37058 1/20 0.40
HSD17B2 P37059 1/20 0.40
HSD17B10 Q99714 1/20 0.39
CNR2 P34972 1/20 0.39
ALPL P05186 1/20 0.39
ALPI P09923 1/20 0.39
ALPG P10696 1/20 0.39
DNMT1 P26358 1/20 0.39
MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10454872 0.86 POLB (0.59) POLBGAAALDH1A1PKMGFER
SCHEMBL9293164 0.85 POLB (0.47) POLBGAAALDH1A1PKMGFER
SCHEMBL1581335 0.82 POLB (0.54) POLBGAAALDH1A1PKMGFER
SCHEMBL69469 0.82 HSD17B10 (0.52) POLBGAAGFERHSD11B1PTGS1
SCHEMBL9341624 0.82 GAA (0.57) POLBGAAALDH1A1PTGS1PTGS2
SCHEMBL68932 0.82 GAA (0.57) POLBGAAALDH1A1PTGS1PTGS2
SCHEMBL29598983 0.82 GAA (0.57) POLBGAAALDH1A1PTGS1PTGS2
SCHEMBL258722 0.78 POLB (0.50) POLBGAAALDH1A1PKMGFER
SCHEMBL10497615 0.77 CA1 (0.44) POLBGAAALDH1A1PKMHSD11B1
SCHEMBL10497574 0.77 CA1 (0.47) POLBGAAALDH1A1PKMHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5077182-A Cyan/magenta/yellow couplers having specific spectral sensitometric properties; negative interlayer effect; color reproduction; graininess; image sharpness FUJI PHOTO FILM CO., LTD. (JP) 1991-12-31 US disclosed
US-5049474-A Color light-sensitive material FUJI PHOTO FILM CO., LTD (JP) 1991-09-17 US disclosed
EP-0281118-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-04-10 EP disclosed
US-4886736-A COUPLERS AND COMPOUND CAPABLE OF RELEASING PHOTOGRAPHICALLY USEFUL GROUP UPON REDUCTION FUJI PHOTO FILM CO., LTD. (JP) 1989-12-12 US disclosed
US-4814261-A Silver halide photographic material containing a development restrainer or a precursor thereof FUJI PHOTO FILM CO., LTD. (JP) 1989-03-21 US disclosed
EP-0281118-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-09-07 EP disclosed