SCHEMBL9293164

SCHEMBL9293164

[O]c1ccc(S(=O)(=O)c2ccc(O)cc2Cl)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
HSD11B1 P28845 12/20 0.43
GAA P10253 2/20 0.42
ALDH1A1 P00352 1/20 0.42
PKM P14618 1/20 0.42
GFER P55789 1/20 0.39
CNR2 P34972 1/20 0.39
HSD17B10 Q99714 1/20 0.38
TTR P02766 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769398 0.85 POLB (0.57) POLBHSD11B1GAAALDH1A1PKM
SCHEMBL10454872 0.84 POLB (0.59) POLBHSD11B1GAAALDH1A1PKM
SCHEMBL69469 0.80 HSD17B10 (0.52) POLBHSD11B1GAAGFERHSD17B10
SCHEMBL8024742 0.76 MAPT (0.48) POLBGAAALDH1A1HSD17B10
SCHEMBL10497615 0.76 CA1 (0.44) POLBHSD11B1GAAALDH1A1PKM
SCHEMBL10497574 0.76 CA1 (0.47) POLBHSD11B1GAAALDH1A1PKM
SCHEMBL1808946 0.71 HSD17B10 (0.50) POLBHSD17B10TTR
SCHEMBL1807426 0.71 ALDH1A1 (0.44) ALDH1A1HSD17B10
SCHEMBL15880399 0.71 TRPV4 (0.53) POLBHSD17B10TTR
SCHEMBL11125511 0.70 ALPL (0.51) POLBHSD11B1GAAALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0500043-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1994-05-04 EP disclosed
US-5302503-A Sulfonylurea-containing coupler for color films; high dye forming rate and color forming density; sharpness; sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1994-04-12 US disclosed
EP-0500043-A1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1992-08-26 EP disclosed
US-5077182-A Cyan/magenta/yellow couplers having specific spectral sensitometric properties; negative interlayer effect; color reproduction; graininess; image sharpness FUJI PHOTO FILM CO., LTD. (JP) 1991-12-31 US disclosed
US-5049474-A Color light-sensitive material FUJI PHOTO FILM CO., LTD (JP) 1991-09-17 US disclosed
EP-0281118-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-04-10 EP disclosed
US-4886736-A COUPLERS AND COMPOUND CAPABLE OF RELEASING PHOTOGRAPHICALLY USEFUL GROUP UPON REDUCTION FUJI PHOTO FILM CO., LTD. (JP) 1989-12-12 US disclosed
US-4814261-A Silver halide photographic material containing a development restrainer or a precursor thereof FUJI PHOTO FILM CO., LTD. (JP) 1989-03-21 US disclosed
EP-0281118-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-09-07 EP disclosed