Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 7/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.67 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.65 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.65 |
| ▸ | HNF4A | P41235 | 2/20 | 0.65 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15509480 | 0.84 | BACE1 (0.54) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL16247702 | 0.84 | AKR1C2 (0.65) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL9245932 | 0.83 | PTPN1 (0.73) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL5437754 | 0.83 | PTPN1 (1.00) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL10479912 | 0.81 | PTPN1 (0.71) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL30763496 | 0.81 | PTPN1 (0.71) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL6842109 | 0.81 | PTPN1 (0.70) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL9651394 | 0.80 | PTPN1 (0.69) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL11674213 | 0.80 | PTPN1 (0.69) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL6809509 | 0.80 | AKR1C2 (1.00) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1444477-A | Thrombopoietin mimetics | SMITHKLINE BEECHAM CORP (US) | 2003-09-24 | — | — | CN | claimed |
| CN-114269756-A | 4-oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds inhibiting EIF4E | 效应疗法股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-1444477-A | Thrombopoietin mimetics | SMITHKLINE BEECHAM CORP (US) | 2003-09-24 | — | — | CN | disclosed |
| US-4999333-A | For facsimile and thermal printing | FUJI PHOTO FILM CO., LTD. (JP) | 1991-03-12 | — | — | US | disclosed |
| US-4134847-A | HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1979-01-16 | — | — | US | disclosed |
| US-4046941-A | PRESSURE SENSITIVE COPYING | SANKO CHEMICAL COMPANY LTD. (JA) | 1977-09-06 | — | — | US | disclosed |
| US-3983292-A | Pressure sensitive recording papers | SANKO CHEMICAL COMPANY LTD. (JA) | 1976-09-28 | — | — | US | disclosed |