Ethylene Glycol

Ethylene Glycol

SCHEMBL9769774

O=C(O)COCC(O)=S.OCCO

nearest known ligand 0.36

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
CTH P32929 1/20 0.36
CBS P35520 1/20 0.36
THPO P40225 1/20 0.36
THRB P10828 1/20 0.35
PTGS1 P23219 1/20 0.33
NPC1 O15118 1/20 0.31
CAMK2A Q9UQM7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29011318 0.92 TSHR (0.41) TSHRCTHCBSTHPOTHRB
SCHEMBL41378 0.92
Hydrochloric Acid SCHEMBL8014197 0.90 THRB (0.43) TSHRCTHCBSTHPOTHRB
SCHEMBL30611336 0.90 TSHR (0.39) TSHRCTHCBSTHPOTHRB
Ammonia Solution, Strong SCHEMBL246434 0.90 TSHR (0.39) TSHRCTHCBSTHPOTHRB
Ammonia Solution, Strong SCHEMBL339618 0.90 TSHR (0.39) TSHRCTHCBSTHPOTHRB
Di(Hydroxyethyl)Ether SCHEMBL28927387 0.89 TSHR (0.43) TSHRCTHCBSTHPOTHRB
Ethylene SCHEMBL28225848 0.87 TSHR (0.38) TSHRCTHCBSTHPOTHRB
Methyl Alcohol SCHEMBL9810528 0.87 PTGS1 (0.38) TSHRCTHCBSTHPOTHRB
Ethylene Glycol SCHEMBL25438740 0.87 TSHR (0.45) TSHRCTHCBSTHPOTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047576-A Polymerizable vinyl compound having polythioether skeleton SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-09-10 US disclosed