SCHEMBL9769798

SCHEMBL9769798

CC(CC(C)(C)C)c1cccc(O)c1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
BID P55957 7/20 0.43
MCL1 Q07820 7/20 0.43
BCL2L1 Q07817 6/20 0.43
BAK1 Q16611 6/20 0.43
KAT8 Q9H7Z6 3/20 0.43
EP300 Q09472 2/20 0.43
KAT5 Q92993 2/20 0.43
SAE1 Q9UBE0 2/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
SLC37A4 O43826 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769887 0.90 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL9769844 0.85 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL25049929 0.81 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL8373593 0.78 TSHR (0.64) CA12CA1CA2CA14TSHR
SCHEMBL4961934 0.78 CA1 (0.61) CA12CA1CA2CA7CA9
SCHEMBL23815704 0.77 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL11138001 0.77 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL5918491 0.71 RIPK1 (0.43) CA1CA2TSHR
SCHEMBL20781114 0.71 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL14321735 0.71 TSHR (0.53) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210228723-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-07-29 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210228723-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ZFX, F13B, GRN CA12 4401/4885CA1 4706/4885CA2 3912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.